A choice where every alternative has significant negative consequences.

(law, narcotics) The particular (usually illicit) substance that a person is addicted to. / The best-choice medication to treat a particular medical problem.

(set theory) One of the axioms of set theory, equivalent to the statement that an arbitrary direct product of non-empty sets is non-empty; any version of said axiom, for example specifying the cardinality of the number of sets from which choices are made.

(public policy, law, ethics) Supportive of a person's right to choose whether or not to have an abortion.

Having such a selection of good choices that deciding which one to pick is difficult.

The most suitable and most optimal choice. / The prime cut. / The one with the highest ranking.

toil and duty chosen in preference to ease and pleasure

plural of axiom of choice

(set theory) A function whose domain is a family of nonempty sets, and which selects a member from each of those sets as its value.

That one has chosen, or wishes to choose.