Used other than figuratively or idiomatically: see up, to, here. / (idiomatic) overwhelmed, busy, buried or swamped / Used as an intensifier

(idiomatic) To have become very frustrated or angry; to have reached the limit of one's patience or forbearance.

(idiomatic) To proceed enthusiastically, vigorously, or expertly.

(intransitive, of two opponents) To confront each other decisively. / (intransitive) To attempt to face or resolve an internal contradiction or difficulty.

(idiomatic, of two or more parties, often with a prepositional phrase) to reach an agreement or settle a dispute.

(idiomatic) To be loved or cared about a great deal by.

(idiomatic) Some things need the active cooperation of two parties; blame is to be laid on both parties in a conflict.

To settle or finish, especially a question or discussion.

Inclined to; having a tendency to. / Having the potential to.

(idiomatic) A much more pressing issue to attend to. / (idiomatic) A higher-valued result or target to reach.