The coach immediately called for a blood substitution when the flanker started bleeding, allowing medics to treat him off the field.

Archivists uncovered several World War I substitution ciphers in the soldier's chest, each revealing a glimpse of private thoughts.

Many coffee shops now offer milk substitutes for customers with lactose intolerance.

Many theologians continue to debate the implications of penal substitution for modern understandings of justice and mercy.

After a tactical change, the coach called one of the players from the substitutes' bench to warm up.

After his doctor warned him about high blood pressure, he switched to a salt substitute when seasoning his food.

Many people with high blood pressure use salt substitutes to reduce sodium intake.

The lab report described a substitution reaction in which a halogen was replaced by a hydroxyl group.

The nucleophilic substitution of the alkyl bromide by hydroxide proceeded with inversion of configuration.

During the lecture on aromatic chemistry, the professor illustrated how electrophilic substitution replaces a hydrogen atom on a benzene ring with an incoming electrophile.