When taken in large doses, the tonic was disadvantageable to villagers, producing nausea and weakness.

The new zoning law disadvantaged small family farms, forcing many to sell their land.

Many students from disadvantaged backgrounds struggle to access top universities.

One disadvantage of remote work is the increased potential for social isolation, which can negatively affect mental health.

The new regulations will disadvantage small businesses by raising compliance costs.

Accepting the offer without negotiation would be disadvantageous to the whole team.

She disadvantages small teams by assigning all the high-stakes tasks to senior members.

Before making a decision, she carefully weighed the disadvantages against the potential benefits.

The disadvantageousness of the contract became clear only after we had already signed.

The new zoning law disadvantageously affected several small businesses on the block.