(slang, humorous) The illness caused by drinking too much alcohol; a hangover.

(idiomatic) It is too late.

A chemical reaction in which an aqueous solution containing glucose, sodium hydroxide and methylene blue turns from colourless to blue upon shaking and then loses its colour after a while. With further shaking, the cycle can be repeated several times.

(UK) To lose courage and determination. / Used other than figuratively or idiomatically: see lose, bottle.

(rare) To acquiesce in some falsehood; to make pretence.

Synonym of bottle flipping

(dated) A man who can drink a lot of alcohol without becoming noticeably drunk.

plural of three-bottle man

A wine bottle that has a capacity of 187.5 ml (a quarter of a bottle), typically used for a single serving of champagne

(Nigeria, slang) moonshine; illicit alcohol