(law) Estrangement or loss of affection between two people who have a claim on each other's affections (such as two spouses or a parent and child) that is willfully caused by interference from a third party.

(artificial intelligence) The study and development of systems and devices that can recognize, interpret, process, and simulate human affects.

(psychology) A form of depression associated with the lack of natural light during the winter months.

(political science, US) the process of steady growth of the mutual dislike between Republicans and Democrats since the 1970s

In an affected manner; hypocritically; with more show than reality. / (obsolete) Lovingly; with tender care. / (obsolete) With intention, intentionally, deliberately.

The state or quality of being affected.

superlative form of affected: most affected

plural of affectedness