(informal) Ellipsis of Down's syndrome.

plural of down-down

(slang) Among the Hash House Harriers, a penalty in which an individual must down his or her drink.

(comparable) From a higher position to a lower one; downwards. / As a down payment. / On paper (or in a durable record). / To the south (as south is at the bottom of typical maps).

From the higher end to the lower of. / From north to south of. / From one end to another of (in any direction); along.

Facing downwards. / At a lower level than before. / (informal) Sad, unhappy, depressed, feeling low. / (normally in the combination 'down with') Sick or ill. / Having a lower score than an opponent.

(transitive) To knock (someone or something) down; to cause to come down; to fell. / (transitive) Specifically, to cause (something in the air) to fall to the ground; to bring down (with a missile etc.).

A negative aspect; a downer, a downside. / (dated) A grudge (on someone). / An act of swallowing an entire drink at once.

(especially southern England) A hill, especially a chalk hill; rolling grassland / (usually in the plural) A field, especially one used for horse racing.

Soft, fluffy immature feathers which grow on young birds. Used as insulating material in duvets, sleeping bags and jackets.