(transitive) To hurt; to put to bodily uneasiness or anguish; to afflict with uneasy sensations of any degree of intensity; to torment; to torture.

(obsolete, cooking) Any of various breads stuffed with a filling.

(countable and uncountable) An ache or bodily suffering, or an instance of this; an unpleasant sensation, resulting from a derangement of functions, disease, or injury by violence; hurt.

A surname.

Used to warn of consequences if a specified act is done or not done: subject to the punishment of (some penalty); or (generally) subject to the circumstance of (some thing).

Acronym of pan-assay interference compound.

Feeling or experiencing pain.

The state or quality of being painful, of causing pain. / The state or quality of being tedious, of requiring great care.

(idiomatic, with infinitive) Making careful effort (to).

Causing pain or distress, either physical or mental. / Afflicted or suffering with pain (of a body part or, formerly, of a person). / Requiring effort or labor; difficult, laborious.