The cleaning spray released an irritant mist that stung our eyes.

The doctor prescribed an irritant to provoke a localized inflammatory response.

Her constant irritableness made it difficult for the team to discuss problems calmly.

The doctor's notes described the rash as irritational rather than infectious, suggesting a reaction to a new detergent.

The constant buzzing and flickering lights were among the worst irritators in the old office.

The constant tapping of his pen irritates everyone in the room.

Her constant irritablenesses made the office a tense place by the end of the week.

Despite the many irritations, she managed to finish the project on time.

I have learned to give irritable hearts the space they need to calm down.

In the nineteenth century, physicians frequently attributed unexplained breathlessness and fainting to an irritable heart.