In the direction or orientation of. / In the manner of. / In the matter of; with regard to. / One at a time, or one thing at a time.

To become wise. / (ergative, slang) Usually with "up", to inform or learn.

Showing good judgement or the benefit of experience. / (colloquial, ironic, sarcastic) Disrespectful. / (colloquial) Aware, informed.

(dialectal) To instruct. / (dialectal) To advise; induce. / (dialectal) To show the way, guide. / (dialectal) To direct the course of, pilot. / (dialectal) To cause to turn.

(archaic) Way, manner, or method.

The state, quality, or measure of being wise; wisdom.

plural of wiseness

(intransitive) To make a sarcastic, flippant, or sardonic comment.

(idiomatic) Used to emphasis following as a piece of significant advice.

(idiomatic) A brief piece of advice.