(Roman Catholicism, theology) A sin which causes the loss of God's grace, leading to eternal damnation, unless the sinner repents, which includes their intent to confess and atone; such a sin is defined as a transgression against one of the Ten Commandments with the full knowledge and deliberate consent of the sinner.

Any of the deadly sins.

Any of the seven deadly sins: anger, greed/avarice, envy, gluttony, lust, pride, and sloth.

(sports) An area where players are temporarily confined while suspended from play following an infringement of the rules of the game.

(sports, usually in passive voice) to send a player off temporarily following an infringement of a rule in a game

(historical) A person (usually a man) who is supposed to take sins of a deceased person upon himself by means of eating a piece of bread, laid for him on the breast of the dead one.

(theology) Sin committed by an individual, in contradistinction to original sin.

(simile) Very original.

(simile) Extremely ugly.

(humorous) Jokingly suggesting that some ostensibly undesirable task or situation has been assigned as a punishment.