The doctor prescribed an irritant to provoke a localized inflammatory response.

He kept irritating his sister by hiding her keys.

The constantly dripping faucet became so irritating that I couldn't concentrate on my work.

Her constant irritableness made it difficult for the team to discuss problems calmly.

The doctor's notes described the rash as irritational rather than infectious, suggesting a reaction to a new detergent.

The constant buzzing and flickering lights were among the worst irritators in the old office.

The constant tapping of his pen irritates everyone in the room.

Her constant irritablenesses made the office a tense place by the end of the week.

Her irritative tone during the meeting made it difficult for colleagues to stay calm.

The lab labeled the unknown compound as an irritative after several volunteers reported burning sensations.