The down-regulation of the receptor significantly reduced cellular responsiveness to the hormone.

The new beverage formula reduced the amount of acidity regulators to meet the stricter label requirements.

The ingredient list names calcium carbonate as an acidity regulator to stabilize the sauce.

The self-regulated thermostat adjusted the temperature based on the room's occupancy and time of day.

No one volunteered for the night watch because Regulation Charlie would inspect every log and punish even the smallest oversight.

Recent research suggests that neuroimmune regulation plays a central role in maintaining metabolic homeostasis during infection.

The agency rushed to finalize the midnight regulations before the new administration took office.

The auditors reviewed several Regulation Charlies to ensure the bank complied with consumer protection standards.

All employees must familiarize themselves with the company's rules and regulations before starting any project.