(Britain) Someone or something that is annoying or frustrating.

(vulgar) Something or someone that causes discomfort or frustration.

(chiefly Britain, slang) Someone or something very annoying.

(Canada, US, informal) A nuisance; a source of trouble or annoyance.

(idiomatic, slang) Someone or something which is annoying, irritating or inconvenient.

One must be willing to endure some inconvenience or discomfort in order to achieve worthwhile goals.

(British spelling, often plural) the pain suffered by a woman in labour during childbirth.

without pain, free of pain.

Racked with pain, in pain, suffering.

that relieves pain