(formal) A title of respect for females used when referring to heads of state, heads of government, governors, ambassadors, certain ecclesiastics, royalty, and others holding equivalent rank.

(obsolete) Pre-eminent superiority; pre-excellence.

Being the proper or truest example of a general name. / Being a quintessential example of a general type.

Because or on account of one's excellence. / Most especially, in particular, most notably (out of a thing or person's other attributes, roles, etc.).