English Dictionary

sildenafil

IPA（発音記号）

/sɪlˈdɛn.ə.fɪl/

名詞

不可算名詞

(pharmacology) A drug that is used in the form of its citrate C₂₂H₃₀N₆O₄S·C₆H₈O₇ to treat erectile dysfunction in males, that by suppressing a phosphodiesterase enzyme also suppresses the enzyme's inhibitory effect on the hormone cyclic GMP, and that enables the cyclic GMP produced during sexual arousal to initiate the muscular and vascular changes which produce an erection. It is marketed under the trademarks Revatio and Viagra.

日本語の意味

シルデナフィル：男性の勃起不全治療に用いられる医薬品。シトレート塩（C₂₂H₃₀N₆O₄S·C₆H₈O₇）の形態で使用され、ホルモンである環状GMPに対するリン酸ジエステラーゼの抑制作用により、性的刺激時の環状GMPの効果が発現し、筋肉や血管の変化を引き起こして勃起を促す。

Before prescribing sildenafil, the doctor reviewed the patient's medical history and current medications to avoid dangerous interactions.

医師は処方する前に、勃起不全の治療薬であるシルデナフィルの危険な相互作用を避けるため、患者の既往歴と現在の服薬状況を確認しました。

意味（1）

(pharmacology) A drug that is used in the form of its citrate C₂₂H₃₀N₆O₄S·C₆H₈O₇ to treat erectile dysfunction in males, that by suppressing a phosphodiesterase enzyme also suppresses the enzyme's inhibitory effect on the hormone cyclic GMP, and that enables the cyclic GMP produced during sexual arousal to initiate the muscular and vascular changes which produce an erection. It is marketed under the trademarks Revatio and Viagra.

Ellis opens a file from his stack. In 1991, he says, Pfizer wanted to test the safety of what came to be known as sildenafil.