最終更新日：2025/11/20
(pharmacology) A drug that is used in the form of its citrate C₂₂H₃₀N₆O₄S·C₆H₈O₇ to treat erectile dysfunction in males, that by suppressing a phosphodiesterase enzyme also suppresses the enzyme's inhibitory effect on the hormone cyclic GMP, and that enables the cyclic GMP produced during sexual arousal to initiate the muscular and vascular changes which produce an erection. It is marketed under the trademarks Revatio and Viagra.
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sildenafil
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元となった辞書の項目
sildenafil
IPA（発音記号）
名詞
不可算名詞
(pharmacology)
A
drug
that
is
used
in
the
form
of
its
citrate
C₂₂H₃₀N₆O₄S·C₆H₈O₇
to
treat
erectile
dysfunction
in
males,
that
by
suppressing
a
phosphodiesterase
enzyme
also
suppresses
the
enzyme's
inhibitory
effect
on
the
hormone
cyclic
GMP,
and
that
enables
the
cyclic
GMP
produced
during
sexual
arousal
to
initiate
the
muscular
and
vascular
changes
which
produce
an
erection.
It
is
marketed
under
the
trademarks
Revatio
and
Viagra.
日本語の意味
シルデナフィル：男性の勃起不全治療に用いられる医薬品。シトレート塩（C₂₂H₃₀N₆O₄S·C₆H₈O₇）の形態で使用され、ホルモンである環状GMPに対するリン酸ジエステラーゼの抑制作用により、性的刺激時の環状GMPの効果が発現し、筋肉や血管の変化を引き起こして勃起を促す。
意味（1）
(pharmacology)
A
drug
that
is
used
in
the
form
of
its
citrate
C₂₂H₃₀N₆O₄S·C₆H₈O₇
to
treat
erectile
dysfunction
in
males,
that
by
suppressing
a
phosphodiesterase
enzyme
also
suppresses
the
enzyme's
inhibitory
effect
on
the
hormone
cyclic
GMP,
and
that
enables
the
cyclic
GMP
produced
during
sexual
arousal
to
initiate
the
muscular
and
vascular
changes
which
produce
an
erection.
It
is
marketed
under
the
trademarks
Revatio
and
Viagra.
