She was unused to the spicy food of the region, so she ate cautiously at every meal.

The lab technician labelled the unused vials and returned them to cold storage.

After the severe storm, many of the hiking trails were unusably waterlogged, forcing us to turn back.

The instruction manual was unuseful, leaving everyone confused.

Despite her careful planning, she couldn't deny the unusefulness of the outdated manual in solving modern problems.

The old theater fell into unuse after the new cinema opened downtown.

The unusability of the new software frustrated the entire team.

After the flood, most of the electronics were unusable.

The unusableness of the old software frustrated the entire team during the product launch.

The unusedness of the heirloom vase made me hesitate to dust it, afraid that handling it would erase its history.