Researchers observed the proteins heterodimerising on the membrane, altering the signaling pathway.

In the signaling cascade discovered last year, protein A heterodimerises with protein B to initiate downstream gene expression.

When exposed to the ligand, the receptor subunits heterodimerised, triggering downstream signaling.

In vitro, the receptor subunits heterodimerise to trigger downstream signaling.

Recent studies have revealed unexpected roles for receptor heterodimerisations in signal transduction pathways across different cell types.

The unexpected heterodimerisation of the receptor subunits altered downstream signaling in the cell line.