I saw a run down building on my way to work.

She lives in a run-down apartment.

Don't look down on others just because they are different.

Could you give me a run-down of your project?

It's important to dumb down complex concepts when explaining them to a general audience.

He decided to pass down his family's traditions to the next generation.

I saw a beautiful house down the road.

One of his own subordinates shot himself in his office after being given a particularly serious dressing down.

I'm not sure what will happen down the line.

I had to turn down his invitation to the party.