A style of architecture, furniture, etc. popular during the reign of Queen Anne. / (attributive) Designating the style of architecture, furniture, etc. popular during the reign of Queen Anne.

(US) In colleges and high schools, a young woman, chosen by her peers, to "reign" over the school's prom and related activities. May reign alongside a prom king.

(slang, LGBT) A homosexual, and often cross-dressing, man acting in an ostentatious and flaunting manner akin to a diva.

(US) In colleges and high schools, a young lady chosen by her peers to "reign" over the traditional activities associated with the Homecoming football game.

(UK, Canada, New Zealand, occasionally Australia) an honorific status officially conferred on senior or meritorious barristers (and occasionally other kinds of lawyer) during the reign of a queen.

(LGBT, originally slang) A person, usually male, who dresses up in women’s clothing and makeup, typically in an exaggerated fashion and for public performance.

(idiomatic, slang, originally LGBT, sometimes derogatory) Someone who prefers sexual partners with large penises.

(slang) A female speedfreak; a woman who abuses stimulating drugs.

A reproductive female (especially the only one) in a colony of bees. / (idiomatic, colloquial, derogatory) The most important or dominant woman in an organisation or situation. / (metaphoric) Stem cell

Pertaining to a larger-than-average dress, blouse, skirt, pant or stocking size for women.