(computing) An instruction or operation that has no effect; a null operation.

(LGBT, of a transgender or transsexual person) Having chosen not to undergo sex reassignment surgery.

(LGBT) A transgender or transsexual person who has chosen not to undergo sex reassignment surgery.

plural of no-op

A woman will make someone suffer if they reject her.

(idiomatic, usually with "with") To have no influence (on); not to be accepted or tolerated.

(idiomatic) Something unexceptional, not noteworthy or special.

(informal, derogatory) One who does not have a social life.

Having no social life.

(transitive, video games) To spend most or all one's time on.