最終更新日：2025/12/06
(biochemistry) A protein structural motif containing three disulfide bridges formed from pairs of cysteine residues. The sections of polypeptide that occur between two of them form a loop through which a third disulfide bond passes, resulting in a rotaxane substructure. This motif stabilizes protein structure and is conserved in proteins across various species.
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cystine knot
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元となった辞書の項目
cystine knot
名詞
(biochemistry)
A
protein
structural
motif
containing
three
disulfide
bridges
formed
from
pairs
of
cysteine
residues.
The
sections
of
polypeptide
that
occur
between
two
of
them
form
a
loop
through
which
a
third
disulfide
bond
passes,
resulting
in
a
rotaxane
substructure.
This
motif
stabilizes
protein
structure
and
is
conserved
in
proteins
across
various
species.
日本語の意味
（生化学）３つのジスルフィド結合を持つタンパク質構造モチーフ。これは、2組のシステイン残基の間に形成されたポリペプチド鎖のセクションがループを作り、さらにそのループを通す形で３番目のジスルフィド結合が形成され、結果的にロタキサン様の部分構造を生じ、タンパク質構造の安定化に寄与する。
意味（1）
(biochemistry)
A
protein
structural
motif
containing
three
disulfide
bridges
formed
from
pairs
of
cysteine
residues.
The
sections
of
polypeptide
that
occur
between
two
of
them
form
a
loop
through
which
a
third
disulfide
bond
passes,
resulting
in
a
rotaxane
substructure.
This
motif
stabilizes
protein
structure
and
is
conserved
in
proteins
across
various
species.
（ plural ）
