Having four legs.

An animal that walks on four legs. / An intersection where two roads cross.

(basketball, US, informal) The four regional champions of the NCAA Division I tournament, one of whom will become the national champion.

(algebraic geometry) Having four dimensions; being measurable along four mutually perpendicular axes.

The cardinal number immediately following twenty-three and preceding twenty-five.

(US, slang) To win something four times consecutively.

(US, slang) A fourth successive win.

The cardinal number immediately following thirty-three and preceding thirty-five.

The cardinal number immediately following forty-three and preceding forty-five.

(slang) A .44 Magnum handgun