The biologist proposed that a macromutation caused the rapid emergence of the novel trait.

The researchers observed a macromutational shift in the virus's antigenic profile after prolonged exposure to the antiviral drug.

Scientists debated whether macromutations could drive the rapid emergence of novel species in isolated island ecosystems.

The macromutationist defended his controversial hypothesis at the symposium, arguing that sudden large-scale genetic changes could drive rapid speciation.

The historian of science explained how macromutationism briefly influenced early twentieth-century debates about the origin of species.

The conference panel debated whether macromutationists could account for the rapid emergence of novel body plans in the fossil record.