English Dictionary

disease enhancement

名詞

(medicine, pathology) A side-effect of a therapeutic treatment, whereby the putative therapeutic agent, instead of alleviating the disease, enhances the pathology. Such as an antibody introduced or incited by the treatment binds to the disease agent, causing it to function better; such as antibodies binding to virus spike proteins and increasing its ability to infect cells.

日本語の意味

治療を目的として投与された薬や治療法が、逆に病気の症状や病態を悪化させる現象。例えば、治療によって誘発された抗体がウイルスのスパイクタンパクに結合し、ウイルスの細胞感染能を高める場合などを指す。

After the experimental vaccine was administered, clinicians reported instances of disease enhancement when certain antibodies unexpectedly increased viral entry into host cells.

実験的なワクチンが投与された後、一部の抗体が予期せずウイルスの宿主細胞への侵入を増加させたことで、治療による病状の悪化が確認されたと臨床医は報告した。

意味（1）

(medicine, pathology) A side-effect of a therapeutic treatment, whereby the putative therapeutic agent, instead of alleviating the disease, enhances the pathology. Such as an antibody introduced or incited by the treatment binds to the disease agent, causing it to function better; such as antibodies binding to virus spike proteins and increasing its ability to infect cells.

disease enhancements （ plural ）