The holiday ended all too soon.

When I go on vacation , I'll rent a car.

She carries on smiling even in the face of adversity.

Despite adversity, the ingenious man achieved worldwide fame.

Adversity is the best school.

The converse is also true.

If people who smoke are deprived of their cigarettes, they get nervous and irritable.

Smoking affects your health.

Short-term effects of smoking include unfitness, wheezing, a general vulnerability to illness, bad breath, bad skin and so on.

Imagine, for the sake of argument, a tribal group in which mother-son incest was countenanced.