At this time, the rationale for the use of ergotamine was that, contrary to the interpretation that had prevailed in earlier years, migraine headache depended on excessive rather than decreased sympathetic activity, and that ergotamine had a sympatheticolytic rather than a sympathomimetic effect.

to relax the muscles or sinews

This ſaid, ſhe wip’d from Venus’ wounded Palm / The ſacred Ichor, and infus’d the Balm.

Poor and content is rich, and rich enough, But riches fineless is as poor as winter To him that ever fears he shall be poor. Good heaven, the souls of all my tribe defend From jealousy!