Why did you bawl out just as I was aiming? Who can aim with a fellow bawling in his ear? I've lost the birds through it.

[…] the more inside-baseball the name, the nerdier the subject matter.

This can be demonstrated in NOD mice in which a point mutation in the autoimmune regulator (Aire) gene results in the reduced expression of P0 in the thymus and a concomitant increase of P0 specific T cells in the periphery. 107 Similarly, autoimmunity is shifted towards the peripheral nerve in another NOD model deficient for isoforms of ICAM-1. 108 Altered expression of ICAM-1 on thymic epithelial cells transforms selection of T cells from a diabetogenic into a neuritogenic repertoire. 108 Studies such as these highlight the critical role of regulatory mechanisms in maintaining immune homeostasis and the impact that changes to regulation can have on the development of disease.

Her driver was new to the country; he mightn't be prepared for the leaping of the yellow water down dry arroyos, swift as the pouncings of a cat, or the snake-like slidings of tons of loosened rock and clay from the steep potreros […]