By ubiquinating Akt, TRAF6 promotes Akt translocation to the plasma membrane, where it becomes phosphorylated.
The hills rose scarlet and gold to the north of the little town, and the westering sun shone ruddily and mystically on the crude new stone and plaster buildings of the dusty forum and the wooden walls of the circus some distance to the east.
At 4pm, the phone went. It was The Sun: 'We hear your daughter's been expelled for cheating at her school exams...' She'd made a remark to a friend at the end of the German exam and had been pulled up for talking. As they left the exam room, she muttered that the teacher was a 'twat'. He heard and flipped—a pretty stupid thing to do, knowing the kids were tired and tense after exams. Instead of dropping it, the teacher complained to the Head and Deb was carpeted.
“Word processors are wonderful to make us more productive, but employers tend to take this to an extreme,” she said. “Some secretaries are very pleased with automation, but it's the larger number whose jobs are deskilled, made more redundant.”