You get the negation of a proposition if you insert not (or some equivalent expression) into it in such a way as to form a contradictory of it.
not
The first task for a crystallographer is to establish the shape of the unit cell.
Miss Thorn began digging up the turf with her lofter: it was a painful moment for me. ¶ “You might at least have tried me, Mrs. Cooke,” I said.
Not long ago, it was difficult to produce photographs of tiny creatures with every part in focus. That’s because the lenses that are excellent at magnifying tiny subjects produce a narrow depth of field. A photo processing technique called focus stacking has changed that.
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