Following deprotonation of the water molecule by a conserved glutamate residue (Glu146), the resulting hydroxide ion attacks the carbonyl carbon to form a Zn²⁺-bound gem-diolate.
It had seemed that the earth now offered nothing further to explorers; that the virgin forest, the untrodden desert, the mapless mountain, the unjourneyed sea were all things of the past […]
Engineers are forging ahead with the final tests on ESA’s Intermediate eXperimental Vehicle, IXV, to check that it can withstand the demanding conditions from liftoff to separation from Vega.
In Lent noblemen and carls alike had got into the traces and pulled the carts of stone themselves.
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