Irene's whole gimmick is that she's the one woman in the world who can outwit Holmes. Although in the actual story, her victory is extremely limited, flanderization takes hold in adaptations.
Radioisotope renography with Tc99m-mercaptoacetyltriglycine indicated marked functional renal impairment.
There is something in the wind, that we cannot get in.
Nights baſhfull Empreſſe, though ſhe often wayne, / As oft repents her darkneſſe ; primes againe ; / And with her circling Hornes does re-embrace / Her brothers wealth, and orbs her ſilver face.
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