I must thank you again and again for the kind wishes expressed, and feel only too happy to know that my poor verses have, perhaps unmeritingly, found approbation in your eyes, an approbation of which they well may feel proud.

Almost as an afterthought, we’re given an origin story for Barney’s alcoholism: he was once a sober, studious, Ivy League-bound high school scholar before Homer forced a beer on him that transformed him into a drooling, slurring, out of control rampaging id.

In the old days, to my commonplace and unobserving mind, he gave no evidences of genius whatsoever. He never read me any of his manuscripts, […], and therefore my lack of detection of his promise may in some degree be pardoned. But he had then none of the oddities and mannerisms which I hold to be inseparable from genius, and which struck my attention in after days when I came in contact with the Celebrity.

As indicated by fMRI, during facial emotional categorization young females with major depressive disorder, MDD, exhibit hyperactivation, whereas young males display hypoactivation in the precuneous brain area [65 ].