These findings, together with previous evidence that heparin stimulates Tau phosphorylation by protein kinases, have been used to argue that sulfated glycosaminoglycans may be a critical factor in the formation of the neurofibrillary tangles.

Chico & Rita opens in the modern era, as an aged, weary Chico shines shoes in his native Cuba. Then a song heard on the radio—a hit he wrote and recorded with Rita in their youth—carries him back to 1948 Havana, where they first met.

The opinion of our shoe manufacturer friends is very definitely that a Mullen test or bursting strength test, which may be useful as an entity in itself, has no relationship at all to lastability of leather.

The importance of the President in our foreign relations, when his power in that regard is considered in connection with his duty to take care that the laws are faithfully executed, and with his duty as Commander-in-Chief to direct the movements of the Army and Navy, may be noted in the authority which President McKinley exercised to take part in the so-called Boxer War, in China. The lawless uprising in that ancient Empire against foreigners, which for the time being overthrew the power of the Imperial Government, exposed to danger the lives of the diplomatic representatives of foreign nations at Pekin, and brought about the murder of one of them. Uniting with other governments, President McKinley, without express Congressional authority, ordered the land and naval forces of the United States into a campaign to rescue the foreign legations which were besieged in Pekin.