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Although Equation 2.45 looks simple, it involves more arithmetic operations as compared to Equations 2.36 and 2.38.
As noted, the proximity of Met356 to Cys125 in tmNrdD is compatible with the reaction mechanism proposed for the majority of class III RNRs, involving a thiosulphuranyl radical [48 ].
Bimanual dissection is performed according to the rules of microsurgery: one surgeon works bimanually to dissect and remove the cyst wall, while a second surgeon drives dynamically the endoscope.
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