Coastal fisheries have been devastated by recurring oxygen depletions during the summer.

Modern stimulated emission depletion microscopes allow researchers to image structures well below the diffraction limit.

Using a stimulated emission depletion microscope, the researchers resolved synaptic structures beyond the diffraction limit by applying a short excitation pulse followed by a depletion pulse tuned to the emission line of the dye.

Recent breakthroughs in fluorophore design have significantly improved the resolution achievable with stimulated emission depletion microscopy.