Plant diterpene cyclases have a similar catalytic motif and betagamma-domain structure together with a third, alpha-domain, forming an alphabetagamma structure, and in H(+)-initiated cyclases, there is an EDxxD-like Mg(2+)/diphosphate binding motif located in the gamma-domain,” wrote R. Cao and colleagues, University of Illinois, Center for Biophysics and Computational Biology. The researchers concluded: “The results support a new view of terpene cyclase structure and function and suggest evolution from ancient (betagamma) bacterial triterpene cyclases to (betagamma) bacterial and thence to (alphabetagamma) plant diterpene cyclases.”

Think of the nights he must have prayed at his kitchen shrine for the success of his marvelous vision and invention—and now here he is tooling along through the streets of maybe Yinchwan with bikes everywhere, elegant, metal goddamned bikes with rubber tires and complex sprockets and chains, and all the people laughing at what a funny thing he’s riding on. People laughing to beat the hinges off of hell because he’s riding something those Yinchwanians wouldn’t even go so far as to call a bicycle . . .

The only time I ever worried was when quarterbacks would run the clock down in the last 20 seconds […]

I wanna puppy!