Substitution is the nomination of substituted heirs, who take place, failing the institute.
In this report, we compare the relative interaction strength of both HSP90α and HSP90β with the transcription factors HSF1 and HIF1α, the kinases ERBB2 and MET, the E3-ubiquitin ligases KEAP1 and RHOBTB2, and the HSP90 inhibitors geldanamycin and ganetespib.
Neither we nor any other organ of English opinion, […] can feel the slightest sympathy or compassion for the Taepings, unless indeed there be any truth in the exquisitely horrible accounts of their massacre by Chinese troops which anonymous correspondents send home here. That they are hostes humani generis, we very willingly admit. But because they are hostes humani generis it does not follow that the whole human race is bound to take up the responsibility of defeating their designs.
His [Maestripieri's] take-home message - that brute power politics is the root of, and the route to, success - looks like corroboration of 'veneer theory'
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