Lung cancer in neversmoker appears to be a distinct entity from lung cancer in smoker, with specific molecular characteristic such as frequent EGFR mutations.

[…] That ſince that time he [Archibald Douglas, 6th Earl of Angus] was become the ſubject of King Henry [VIII] of England, his Majeſty's [James V of Scotland's] greateſt enemy; and was now the cauſe of all the Inroads made by the English into Scotland: […]

A long sicknesse will weary friends at last; but a pestilentiall sicknes auerts them from the beginning.

No, no, I was too prudent when I was young to risk the expenses of a bankrupt cart, and now I am old I am too wise to attempt the difficult art of driving one.