Coordinate term: Malay boot
Would you please cut the cake?
Most of the Squattocracy are members of “The Club,” and therefore know who are the chief agreeable idlers (I mean gentlemen who are not oppressed with business) to whom to introduce a stranger.
ADME and chemical reactivity-related toxicity is low, while biological receptor activity is of higher dimension in chemistry space, and this is partly explainable by evolutionary pressures on ADME to deal with endobiotics and exobiotics.
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