The greatest difficulty lies in treating patients with chronic pain.

After lights-out, I clipped the booklight to the cover and continued reading.

A more conservative approach, particularly if your author is a skilled computer user, would be to replace the problem characters with simple words or codes that are guaranteed to transfer successfully between computers. For example, you could replace é with e-acute if that particular character is causing problems. […] The author could then do a search and replace to change all instances of e-acute back to é before publication.

Scales of the back small, unicarinated