Objections to the bulldog clip are that, in students' hands at least, it is more likely to do damage and lead to clotting than is the thread-loop, and that, on account of its small size and liability to be left by the student in the wound, it is apt to be lost, e.g. thrown away with the carcase when the tables are cleared after the class-meeting. A recurrent item of expense in working the class is avoided by dispensing with the bulldog clip.

'Fear not the doomsome words of yon jobbardly Jeremiah, Master Plowman. He maketh merry with us all oft and anon, and 'twill be to his own undoing.

For all subsequent phases, we used a fully web-based recruitment and data collection process comprising signatureless electronic consent (e-consent) form, registration form and questionnaire (Table 1).

Another possible physiological role for a hyperpolarization-activated inward current could be in the postburst hyperpolarization that is characteristic of parasol cells.