Perhaps the most interesting early description of one of the many variants of the guaiacan treatment is that of Nicholas Monardes who wrote of the cure in 1574.

climb stairs two at a time

For now there are ſprung up a wiſer generation in this kind, who have the Art to coy the fonder ſort into their nets

The stability of the mesophases for the polypedes and multipedes is reported in Table 17.