CMS

(computing) Initialism of content management system.

(telecommunications) Initialism of call management system.

(education) Initialism of career management skills.

(computing) Initialism of Color management system.

(computing) Initialism of Conversational Monitor System.

(video games) Initialism of construction and management simulation: a style of game that involves planning and managing a population of citizens in a town or similar, without direct control of characters

(physics, atom) Initialism of Compact Muon Solenoid.