senescence

Organized shuffleboard has always filled me with dread. Everything about it suggests infirm senescence and death: it’s like it’s a game played on the skin of a void and the rasp of the sliding puck is the sound of that skin getting abraded away bit by bit.

Tests in mice found that inducing senescence in bile duct cells - mimicking the process seen in human bile duct disease - led to liver scarring and damage of liver function.