extremity

[B]eſtowe your love on him, who, were it not to do you ſervice, would through the extremitie of love rather wiſh to die then live.

The Fort on the Mount St. Catherine after a Month's Siege was reduc'd to ſuch Extremitys, that they who defended it were forc'd to treat about a Surrender: and Aug. 29. 'twas agreed between the Engliſh Commiſſioners, Edward Earl of Mortaigne, Thomas Earl of Salisbury, and Fitz-Hugh, and the French Commiſſioners, the Sieur Nobles Lieutenant of Guy de Bouteil, which the Sieurs De Buſſon and de Graville, in the Name of the Gariſon, that they would deliver up the Abby and Fortreſs of St. Catherine on the Thurſday following, on condition of having only their Lives ſpar'd.

Guillain–Barré syndrome causes one to not be able to move one’s extremities.

The danger of wounds of the extremities consists in the injury done to the blood-vessels, nerves, articulations, and bones.