The historical significance of this event cannot be overstated.

Their concert was a big hit.

Antiretroviral drugs are used to treat HIV infection.

The cathedral is a holy place of worship.

She saw a homeless man sleeping on the park bench.

He is known for his honest and trustworthy nature.

Honestly, I don't know what to do.

Honesty is the best policy.

They went on a honeymoon to Hawaii.

Yes. And it's only a hop, skip and a jump to the nearest mall.