Last Updated:2025/12/31
Sentence
A
potential
explanation
is
that
the
favorable
prognostic
impact
of
PD-L1
upregulation
in
these
conditions
may
indicate
the
presence
of
a
mixed
immune
cell
infiltrate
containing
cytotoxic
and
regulatory
T
cells
and
reflect
a
partially
dysbalanced
local
cellular
immune
response,
which
still
contributes
to
antitumor
immune
control.
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A potential explanation is that the favorable prognostic impact of PD-L1 upregulation in these conditions may indicate the presence of a mixed immune cell infiltrate containing cytotoxic and regulatory T cells and reflect a partially dysbalanced local cellular immune response, which still contributes to antitumor immune control.
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