Last Updated:2025/11/25

Researchers found that reduced glucocerebrosidase activity leads to lipid accumulation in macrophages, contributing to Gaucher's disease.

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Researchers found that reduced glucocerebrosidase activity leads to lipid accumulation in macrophages, contributing to Gaucher's disease.

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研究者たちは、グルコシルセラミドのβ-グルコシド結合を加水分解する酵素の活性低下がマクロファージ内の脂質蓄積を引き起こし、ゴーシェ病に寄与することを明らかにした。

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